There are about 528,000 new cases of cervical cancer every year in the world, and China accounts for 1/4
Statistics of women undergoing gynecological testing, the total infection rate of HPV is 26.8%
Women are infected at least once in their lifetime, 80% chance of one HPV subtype
Women with a strong enough immune system (80%-90%) will clear the virus through autoimmunity 9-15 months after being infected with HPV
HPV also causes 40% of vaginal and penile cancers, 90% of anal cancers, and 12% of oropharyngeal cancers
The overall genital HPV infection rate in men is as high as 45.2%
Both men and women over the age of nine can be vaccinated
Prevent HPV6, 11, 16, 18, 31, 33, 45, 52, 58 types of viruses
Recognized by US FDA and World Health Organization WHO
Over 200 million Gardasil vaccines have been vaccinated
Allergic to vaccine components (protein/yeast)
Pregnant women, breastfeeding women
Acute disease period (vaccinated after recovery)
Introduction of Drug Information
|Human Papillomavirus 9-valent Vaccine, Recombinant
|GARDASIL 9, Recombinant Human Papillomavirus 9-valent Vaccine
|GARDASIL9 is a vaccine indicated in women and men 9 through 45 years of age for the prevention of the following diseases: Cervical, vulvar, vaginal, anal, oropharyngeal and other head and neck cancers.
|【Dosage and Administration】
|Inoculate 3 doses according to the immunization schedule of 0,2,6 months. According to clinical study data, the interval between the second dose and the first dose is at least 1 month, and the interval between the third dose and the second dose is at least 3 months, and all 3 doses should be completed within one year.
|Pain, redness, swelling, fever, dizziness, headache, nausea, muscle and joint pain, fainting, etc. at the injection site.
|Anyone who is allergic to the ingredients of GARDASIL 9 or GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant], including those severely allergic to yeast, should not receive the vaccine. GARDASIL 9 was not studied in women who knew they were pregnant.
Before vaccination, you must carefully understand the effectiveness and safety of the vaccine (including possible adverse reactions) and contraindications.
After inoculation, you must stay for 15 to 30 minutes and leave after no other reaction.
Once adverse reactions occur, actively cooperate with the vaccination staff to do a good job in handling the reactions.
After the injection of the 9-valent vaccine, if you have sex, you need to do annual cervical cancer screening, because the 9-valent vaccine cannot prevent all cervical cancers.
Age of vaccination: People aged 9 years and above, both male and female.
Alcohol is prohibited on the day of vaccination.
|【People who should not be vaccinated】
|(1) Acute infection period; allergic to vaccine components and proteins; have a pregnancy plan in the short term; pregnant women; pay attention to contraception during vaccination.
(2) Patients with vulvar, cervical precancerous lesions or cervical cancer.
Colds and fevers cannot be vaccinated.
|Store refrigerated at 2 to 8°C (36 to 46°F). Do not freeze. Protect from light.
|【Mechanism of Action】
The nine-valent HPV vaccine has good immunogenicity. After completing the 3-dose vaccination program, the seroconversion rate of related types of HPV can reach almost 100%.
One month after the completion of the vaccination program, the peak geometric mean titer of the antibody could reach 100 times the antibody level after natural infection, and in the next 2 months, this value decreased to 10 times and maintained at a plateau. Vaccine antibody levels are maintained for at least 4 years.
What diseases can HPV 9-valent Vaccine prevent?
GARDASIL 9 (Human Papillomavirus 9-valent Vaccine, Recombinant) helps protect individuals ages 9 to 45 against the following diseases caused by 9 types of HPV: cervical, vaginal, and vulvar cancers in females, anal cancer, certain head and neck cancers, such as throat and back of mouth cancers and genital warts in both males and females.
Can I get the HPV vaccine during menstruation?
Although the guidelines do not mention whether the HPV vaccine can be vaccinated during the menstrual period, according to the basic principles of HPV vaccination, the menstrual period can also be vaccinated.
Can men also get the HPV vaccine?
Men can also be vaccinated. GARDASIL 9 also applies to men aged 9-45.
HPV positive, is it still useful to get vaccinated? Can vaccines cure it?
The HPV vaccine cannot remove the HPV virus that has been infected, but the body will produce an immune effect after the vaccine is injected, reducing the risk of re-infection.
Do I need an HPV test before I get the vaccine?
No need, no matter what the test results are, it will not affect whether you can be vaccinated.
How long is the validity period after vaccination? Do you need to replant?
Several studies have shown that the HPV vaccine provides durable protection against HPV-related disease, and revaccination is not necessary. Remember to do regular cervical cancer screenings.
Will I get cervical cancer after getting vaccinated?
The HPV vaccine does not prevent cervical cancer 100%. Cervical cancer screening should be done regularly regardless of whether you are vaccinated or not.
Can missed vaccines be re-vaccinated? Can I get vaccinated in advance?
If the vaccine cannot be vaccinated on time due to special circumstances, the US Centers for Disease Control and Prevention recommends that the vaccination can be continued no matter how long the interruption is, and the remaining doses only need to be completed, and there is no need to restart. However, pre-vaccination is not recommended.
Can I still get the 4 or 9 HPV vaccine if I have had the 2-valent or 4-valent HPV vaccine?
Yes, different types of vaccines need to be separated by at least 12 months
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